|
|
|
| |
|
|
|
|
| |
Christopher Garcia, Ph.D.
Assistant Professor, HHMI Investigator
Stanford University School of Medicine
2001 Scholar
|
|
|
Christopher Garcia, Ph.D.: We study the structure and function
of proteins, and protein-protein interactions, that play important
roles in mammalian biology, human health, and disease. We primarily
explore molecular and mechanistic questions pertaining to cell surface
receptor recognition and signaling in the Immune and Nervous systems.
We seek to understand how these molecular events coordinate with
the higher order physiology of the cell. MORE
|
|
| |
|
|
|
|
|
| |
|
Christine Jacobs-Wagner, Ph.D.: One of the central
processes in cellular differentiation is the translation of
genetic information into spatial organization to produce two
daughter cells with different cell fate through asymmetric
cell divisions. To understand the regulatory principles of
positional information and cellular asymmetry, we use a simple
prokaryotic model system, Caulobacter crescentus, whose life
cycle depends on obligate steps of cell differentiation and
asymmetric cell division. This simple bacterial system provides
sophisticated genetics and biochemistry, ease of obtaining
synchronized cell cycle cultures, new cytology tools to study
molecule positioning and dynamics in live cells, and post-genomic
techniques. MORE
|
|
|
|
Christine Jacobs-Wagner, Ph.D.
Maxine F. Singer Assistant Professor
Department of Molecular,
Cellular & Developmental Biology
Yale University
2003 Scholar
|
|
| |
|
|
|
|
|
| |
Antony Rosen, MB ChB
Mary Betty Stevens Professor of Medicine, Director
Director of Division of Rheumatology
Johns Hopkins University
1995 Scholar
|
|
|
Antony Rosen, MB ChB: My laboratory works on
the mechanisms underlying autoimmune rheumatic diseases, with a
specific focus on changes in autoantigen structure during differentiation
and various forms of cell death. Understanding the in vivo sources
of the antigens that drive autoimmunity, and the mechanisms whereby
such molecules become available to the immune system, are critical
for rational therapy. MORE
|
|
| |
|
|
|
|
|
|
The
Pew Scholars Program in the Biomedical Sciences
is designed to support young investigators of outstanding promise in the
basic and clinical sciences relevant to the advancement of human health.
The funding of the awards is provided by The
Pew Charitable Trusts.
MORE
|
