| |
| 
| | | | | |
| |
Christopher
Garcia, Ph.D.
Assistant Professor, HHMI Investigator
Stanford University
School of Medicine
2001 Scholar | | |
Christopher Garcia, Ph.D.: We study the structure and function of proteins,
and protein-protein interactions, that play important roles in mammalian biology,
human health, and disease. We primarily explore molecular and mechanistic questions
pertaining to cell surface receptor recognition and signaling in the Immune and
Nervous systems. We seek to understand how these molecular events coordinate with
the higher order physiology of the cell. MORE | |
| | | | | | |
| |
| Christine Jacobs-Wagner, Ph.D.: One of the
central processes in cellular differentiation is the translation of genetic information
into spatial organization to produce two daughter cells with different cell fate
through asymmetric cell divisions. To understand the regulatory principles of
positional information and cellular asymmetry, we use a simple prokaryotic model
system, Caulobacter crescentus, whose life cycle depends on obligate steps of
cell differentiation and asymmetric cell division. This simple bacterial system
provides sophisticated genetics and biochemistry, ease of obtaining synchronized
cell cycle cultures, new cytology tools to study molecule positioning and dynamics
in live cells, and post-genomic techniques. MORE
| | | |
Christine
Jacobs-Wagner, Ph.D.
Maxine F. Singer Assistant Professor
Department
of Molecular,
Cellular & Developmental Biology
Yale University 2003
Scholar
| |
| | | | | | |
| |
Antony Rosen, MB ChB
Mary Betty Stevens
Professor of Medicine, Director
Director of Division of Rheumatology
Johns
Hopkins University
1995 Scholar
| | |
Antony Rosen, MB ChB: My laboratory
works on the mechanisms underlying autoimmune rheumatic diseases, with a specific
focus on changes in autoantigen structure during differentiation and various forms
of cell death. Understanding the in vivo sources of the antigens that drive autoimmunity,
and the mechanisms whereby such molecules become available to the immune system,
are critical for rational therapy. MORE | |
| | | | | | |
|
The
Pew Scholars Program in the Biomedical Sciences
is designed to support young investigators of outstanding promise in the basic
and clinical sciences relevant to the advancement of human health. The funding
of the awards is provided by The Pew Charitable
Trusts. MORE |
